Sonobe S, Kitabatake M, Hara A, Konda M, Ouji-Sageshima N, Terada-Ikeda C, Furukawa R, Imakita N, Oda A, Takeda M, Takamura S, Inoue S, Kunkel SL, Kawaguchi M, Ito T. The critical role of the histone modification enzyme Setdb2 in the pathogenesis of acute respiratory distress syndrome.
Shock (In press)
Saito S, Kitabatake M, Ouji-Sageshima N, Ogawa T, Oda A, Nishimura T, Nishioka T, Fushimi S, Hara A, Shichino S, Kumamoto M, Hontsu S, Kawaguchi T, Ueha S, Sawabata N, Muro S, Matsushima K, Ito T. Angiopoietin-like 4 is a critical regulator of fibroblasts during pulmonary fibrosis development.
Am J Respir Cell Mol Biol (In press)
Matsumura Y, Kitabatake M, Kayano SI, Ito T. Dietary Phenolic Compounds: Their Health Benefits and Association with the Gut Microbiota.
Antioxidants, 12: 880 (2023)
Oda A, Furukawa S, Kitabatake M, Ouji-Sageshima N, Sonobe S, Horiuchi K, Nakajima Y, Ogiwara K, Goitsuka R, Shima M, Ito T, Nogami K. The spleen is the major site for the development and expansion of inhibitor producing-cells in hemophilia A mice upon FVIII infusion developing high-titer inhibitor.
Thromb Res, S0049-3848: 00077-4 (2023)
Iwabuchi S, Tsukahara T, Okayama T, Kitabatake M, Motobayashi H, Shichino S, Imafuku T, Yamaji K, Miyamoto K, Tamura S, Ueha S, Ito T, Murata SI, Kondo T, Ikeo K, Suzuki Y, Matsushima K, Kohara M, Torigoe T, Yamaue H, Hashimoto S. B cell receptor repertoire analysis from autopsy samples of COVID-19 patients.
Front Immunol, 14: 1034978 (2023)
Tanaka T, Okuda H, Isonishi A, Terada Y, Kitabatake M, Shinjo T, Nishimura K, Takemura S, Furue H, Ito T, Tatsumi K, Wanaka A. Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25-Nrf2 pathway.
Nat Immunol, 24: 439-451 (2023)
Kitabatake M, Ouji-Sageshima N, Sonobe S, Furukawa R, Konda M, Hara A, Aoki H, Suzuki Y, Imakita N, Nakano A, Fujita Y, Shichino S, Nakano R, Ueha S, Kasahara K, Muro S, Yano H, Matsushima K, Ito T. Transition of Antibody Titers after SARS-CoV-2 mRNA Vaccination in Japanese Healthcare Workers.
Jpn J Infect Dis, 76: 72-76 (2023)
Kawasaki T, Ikegawa M, Yunoki K, Otani H, Ori D, Ishii KJ, Kuroda E, Takamura S, Kitabatake M, Ito T, Isotani A, Kawai T. Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung.
Cell Rep, 41: 111828 (2022)
Ouji-Sageshima N, Kitabatake M, Fushimi S, Suzuki S, Fukui Y, Furukawa R, Ito T. Lipopolysaccharide from Yoshino cedar trees (Cryptomeria japonica) induces high levels of human macrophage polarization.
J Wood Sci, 68: 63 (2022)
Sawabata N, Kawaguchi T, Watanabe T, Yohikawa D, Ouji-Sageshima N, Ito T. Pure Solid Pattern of Non-Small Cell Lung Cancer and Clustered Circulating Tumor Cells.
Cancers, 14: 4514 (2022)
Ueha R, Ito T, Ueha S, Furukawa R, Kitabatake M, Ouji-Sageshima N, Uranaka T, Tanaka H, Nishijima H, Kondo K, Yamasoba T. Evidence for the spread of SARS-CoV-2 and olfactory cell lineage impairment in close-contact infection Syrian hamster models.
Front Cell Infect Microbiol, 12: 1019723 (2022)
Morita K, Sawabata N, Tatsumi S, Fujii T, Nishikawa T, Kawaguchi T, Arakane T, Tominaga Y, Sakaguchi H, Kobayashi T, Hontsu S, Yamamoto Y, Fujioka N, Ouji-Sageshima N, Ito T, Ohbayashi C. Verification of A New Filter for Isolation of Circulating Tumor Cells by Only Blood Filtration.
Anticancer Res, 42: 4305-4310 (2022)
Shichino S, Ueha S, Hashimoto S, Ogawa T, Aoki H, Wu B, Chen CY, Kitabatake M, Ouji-Sageshima N, Sawabata N, Kawaguchi T, Okayama T, Sugihara E, Hontsu S, Ito T, Iwata Y, Wada T, Ikeo K, Sato TA, Matsushima K. TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.
Commun Biol, 5: 602 (2022)
Mochida N, Matsumura Y, Kitabatake M, Ito T, Kayano SI, Kikuzaki H. Antioxidant Potential of Non-Extractable Fractions of Dried Persimmon (Diospyros kaki Thunb.) in Streptozotocin-Induced Diabetic Rats.
Antioxidants, 11: 1555 (2022)
Ueha R, Ito T, Furukawa R, Kitabatake M, Ouji-Sageshima N, Ueha S, Koyama M, Uranaka T, Kondo K, Yamasoba T. Oral SARS-CoV-2 Inoculation Causes Nasal Viral Infection Leading to Olfactory Bulb Infection: An Experimental Study.
Front Cell Infect Microbiol, 12: 924725 (2022)
Furukawa R, Kitabatake M, Ouji-Sageshima N, Suzuki Y, Nakano A, Matsumura Y, Nakano R, Kasahara K, Kubo K, Kayano SI, Yano H, Ito T. Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model. Sci Rep, 11: 23695 (2021)
Fujioka N, Kitabatake M, Ouji-Sageshima N, Ibaraki T, Kumamoto M, Fujita Y, Hontsu S, Yamauchi M, Yoshikawa M, Muro S, Ito T. Human Adipose-Derived Mesenchymal Stem Cells Ameliorate Elastase-Induced Emphysema in Mice by Mesenchymal-Epithelial Transition. Int J Chron Obstruct Pulmon Dis, 16: 2783-2793 (2021)
Kitabatake M, Matsumura Y, Ouji-Sageshima N, Nishioka T, Hara A, Kayano SI, Ito T. Persimmon-derived tannin ameliorates the pathogenesis of ulcerative colitis in a murine model through inhibition of the inflammatory response and alteration of microbiota. Sci Rep, 11: 7286 (2021)
Kitabatake M, Ouji-Sageshima N, Sonobe S, Furukawa R, Konda M, Hara A, Aoki H, Suzuki S, Imakita N, Nakano A, Fujita Y, Shichino S, Nakano R, Ueha S, Kasahara K, Muro S, Yano H, Matsushima K, Ito T. Transition of antibody titers after the SARS-CoV-2 mRNA vaccine in Japanese healthcare workers. medRxiv, doi: https://doi.org/10.1101/2021.12.28.21268435 (2021)
Sawabata N, Nakane S, Yoshikawa D, Watanabe T, Kawaguchi T, Ouji-Sageshima N, Kushibe K, Ito T. Vein-first Lobectomy for Lung Cancer Assessed According to the Status of Clustered Circulating Tumour Cells. Cancer Diag and Prog, 1: 443-450 (2021)
Makino A, Shibata T, Nagayasu M, Hosoya I, Nishimura T, Nakano C, Nagata K, Ito T, Takahashi Y, Nakamura S. RSV infection-elicited high MMP-12-producing macrophages exacerbate allergic airway inflammation with neutrophil infiltration. iScience, 24: 103201 (2021)
Oda S, Fujisawa M, Chunning L, Ito T, Yamaguchi T, Yoshimura T, Matsukawa A. Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder. PLoS One, 16: e0254289 (2021)
Tatsumi K, Kinugawa K, Isonishi A, Kitabatake M, Okuda H, Takemura S, Tanaka T, Mori E, Wanaka A. Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain. Mol Brain, 14: 163 (2021)
Terada-Ikeda C*, Kitabatake M*, Hiraku A, Kato K, Yasui S, Imakita N, Ouji-Sageshima N, Iwabuchi N, Hamada K, Ito T. Maternal supplementation with Bifidobacterium breve M-16V prevents their offspring from allergic airway inflammation accelerated by the prenatal exposure to an air pollutant aerosol. PLoS One, 15: e0238923 (2020) (*equally contributed)
Kawara A, Mizuta R, Fujisawa M, Ito T, Li C, Nakamura K, Sun C, Kuwabara M, Kitabatake M, Yoshimura T, Matsukawa A. Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin. Sci Rep, 10: 16490 (2020)
Shibata T, Makino A, Ogata R, Nakamura S, Ito T, Nagata K, Terauchi Y, Oishi T, Fujieda M, Takahashi Y, Ato M. Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization. J Clin Invest, 130: 3021-3037 (2020)
Sawabata N, Nakamura T, Kawaguchi T, Watanabe T, Ouji-Sageshima N, Ito T, Taniguchi S. Circulating tumor cells detected only after surgery for non-small cell lung cancer: is it a predictor of recurrence? J Thorac Dis, 12: 4623-4632 (2020)
Yoshimizu Y*, Hara A*, Sakaguchi S, Ohkura N. VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data. Bioinformatics, btaa859 (2020) (*equally contributed)
Imakita N, Kitabatake M, Ouji-Sageshima N, Hara A, Morita-Takemura S, Kasahara K, Matsukawa A, Wanaka A, Mikasa K, Ito T. Abrogated Caveolin-1 expression via histone modification enzyme Setdb2 regulates brain edema in a mouse model of influenza-associated encephalopathy. Sci Rep, 9: 284 (2019)
Morita-Takemura S, Nakahara K, Hasegawa-Ishii S, Isonishi A, Tatsumi K, Okuda H, Tanaka T, Kitabatake M, Ito T, Wanaka A. J Neuroinflammation, 16: 39 (2019)
Tachibana T, Orita Y, Gion Y, Miki K, Ikegami K, Marunaka H, Makino T, Akagi Y, Akisada N, Tsumura M, Ito T, Yoshino T, Nishizaki K, Sato Y. Young adult patients with squamous cell carcinoma of the tongue strongly express p16 without human papillomavirus infection. Acta Otolaryngol, 139: 80-84 (2019)
Kira T, Akahane M, Ouji-Sageshima N, Shimizu T, Onishi T, Omokawa S, Ito T, Tanaka Y. Osteogenesis of osteogenic matrix cell sheets preserved in culture medium in a rat model. Cell Transplant, 27: 1281-1288 (2018)
Matsumura Y, Kitabatake M, Ouji-Sageshima N, Yasui S, Mochida N, Nakano R, Kasahara K, Tomoda K, Yano H, Kayano SI, Ito T. Persimmon-derived tannin has bacteriostatic and anti-inflammatory activity in a murine model of Mycobacterium avium complex (MAC) disease. PLoS One, 12: e0183489 (2017)
Kai Y, Tomoda K, Yoneyama H, Kitabatake M, Nakamura A, Ito T, Yoshikawa M, Kimura H. Silencing of Carbohydrate Sulfotransferase 15 Hinders Murine Pulmonary Fibrosis Development. Mol Ther Nucleic Acids, 6: 163-172 (2017)
Itakura J, Sato M, Ito T, Mino M, Fushimi S, Takahashi S, Yoshimura T, Matsukawa A. Spred2-deficiecy Protects Mice from Polymicrobial Septic Peritonitis by Enhancing Inflammation and Bacterial Clearance. Sci Rep, 7: 12833 (2017)
Miki K, Orita Y, Gion Y, Takao S, Ohno K, Takeuchi M, Ito T, Minoura A, Tachibana T, Marunaka H, Makino T, Matsukawa A, Nishizaki K, Yoshino T, Sato Y. Tumor-Associated Macrophages in the Development of 4-Nitroquinoline-1-Oxide-Induced Tongue Squamous Cell Carcinoma in a Mouse Model. Oncology, 93: 204-212 (2017)
Ito T, Itakura J, Takahashi S, Sato M, Mino M, Fushimi S, Yamada M, Morishima T, Kunkel SL, Matsukawa A. Sprouty-related Ena/VASP homology 1-domain-containing protein-2 (Spred-2) critically regulates influenza A virus (H1N1)-induced pneumonia. Crit Care Med, 44: e530-543 (2016)
Ouji-Sageshima N, Yuui K, Nakanishi M, Takeda N, Odawara Y, Yamashita M, Iwayama H, Awai K, Hashimoto H, Geraghty DE, Ishitani A, Hatake K, Ito T. sHLA-G and sHLA-I levels in Follicular Fluid are Uncorrelated With Successful Implantation. J Reprod Immunol, 113: 16-21 (2016)
Ouji-Sageshima N, Geraghty DE, Ishitani A, Hatake K, Ito T. Establishment of optimized ELISA system specific for HLA-G in body fluids. HLA, 88: 293-299 (2016)
Matsumura Y, Ito T, Yano H, Kita E, Mikasa K, Okada M, Furutani A, Murono Y, Shibata M, Nishii Y, Kayano S. Antioxidant potential in non-extractable fractions of dried persimmon (Diospyros kaki Thunb.). Food Chem, 202: 99-103 (2016)
Matsumura Y, Ito T, Yano H, Kita E, Mikasa K, Okada M, Furutani A, Murono Y, Shibata M, Nishii Y, Kayano S. Data in support of antioxidant activities of the non-extractable fraction of dried persimmon (Diospyros kaki Thunb.). Data Brief, 8: 1247-1254 (2016)
Takahashi S, Yoshimura T, Ohkura T, Fujisawa M, Fushimi S, Ito T, Itakura J, Hiraoka S, Okada H, Yamamoto K, Matsukawa A. A Novel Role of Spred2 in the Colonic Epithelial Cell Homeostasis and Inflammation. Sci Rep, 6: 37531 (2016)
Miki K, Orita Y, Gion Y, Takao S, Ohno K, Takeuchi M, Ito T, Hanakawa H, Tachibana T, Marunaka H, Makino T, Minoura A, Matsukawa A, Nishizaki K, Yoshino T, Sato Y. Regulatory T cells function at the early stage of tumor progression in a mouse model of tongue squamous cell carcinoma. Cancer Immunol Immunother, 65: 1401-1410 (2016)
Yasui F, Itoh Y, Ikejiri A, Kitabatake M, Sakaguchi N, Munekata K, Shichinohe S, Hayashi Y, Ishigaki H, Nakayama M, Sakoda Y, Kida H, Ogasawara K, Kohara M. Sensitization with vaccinia virus encoding H5N1 hemagglutinin restores immune potential against H5N1 influenza virus. Sci Rep, 6; 37915 (2016)
Schaller M, Ito T, Allen RM, Kroetz D, Kittan N, Ptaschinski C, Cavassani K, Carson WF 4th, Godessart N, Grembecka J, Cierpicki T, Dou Y, Kunkel SL. Epigenetic regulation of IL-12-dependent T cell proliferation. J Leukoc Biol, 98: 601-613 (2015)
Ohno K, Sato Y, Ohshima K, Takata K, Miyata-Takata T, Takeuchi M, Gion Y, Tachibana T, Orita Y, Ito T, Swerdlow SH, Yoshino T. A subset of ocular adnexal marginal zone lymphomas may arise in association with IgG4-related disease. Sci Rep, 5: 13539 (2015)
Kroetz DN, Allen RM, Schaller MA, Cavallaro C, Ito T, Kunkel SL. Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection. PLoS Pathog, 11: e1005338 (2015)
Kitabatake M, Soma M, Zhang T, Kuwahara K, Fukushima Y, Nojima T, Kitamura D, Sakaguchi N.
JNK Regulatory Molecule G5PR Induces IgG Autoantibody-Producing Plasmablasts from Peritoneal B1a Cells. J Immunol, 194; 1480-1488 (2015)
Xu Y, Ito T, Fushimi S, Takahashi S, Itakura J, Kimura R, Sato M, Mino M, Yoshimura A, Matsukawa A.
Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice. PLoS One, 9; e108914 (2014)
Liu T, Yu H, Ullenbruch M, Jin H, Ito T, Wu Z, Liu J, Phan SH.
The in vivo fibrotic role of FIZZ1 in pulmonary fibrosis. PLoS One, 9; e88362 (2014)
Takeuchi M, Sato Y, Ohno K, Tanaka S, Takata K, Gion Y, Orita Y, Ito T, Tachibana T, Yoshino T.
T helper 2 and regulatory T-cell cytokine production by mast cells: a key factor in the pathogenesis of IgG4-related disease. Mod Pathol, 27; 1126-1136 (2014)
Hanakawa H, Orita Y, Sato Y, Takeuchi M, Ohno K, Gion Y, Tsukahara K, Tamamura R, Ito T, Nagatsuka H, Nishizaki K, Yoshino T.
Regulatory T-cell infiltration in tongue squamous cell carcinoma. Acta Otolaryngol, 134; 859-864 (2014)
Yasui F, Kohara M, Kitabatake M, Nishiwaki T, Fujii H, Tateno C, Yoneda M, Morita K, Matsushima K, Koyasu S, Kai C.
Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus. Virology, 454-455:157-168 (2014)
Nakazawa T, Nakamura M, Park YS, Motoyama Y, Hironaka Y, Nishimura F, Nakagawa I, Yamada S, Matsuda R, Tamura K, Sugimoto T, Takeshima Y, Marutani A, Tsujimura T, Ouji N, Ouji Y, Yoshikawa M, Nakase H.
Cytotoxic human peripheral blood-derived γδT cells kill glioblastoma cell lines: implications for cell-based immunotherapy for patients with glioblastoma. J Neurooncol, 116; 31-39 (2014)
Saito F, Ito T, Connett JM, Schaller MA, Carson WF 4th, Hogaboam CM, Rochford R, Kunkel SL.
MHV68 Latency Modulates the Host Immune Response to Influenza A Virus. Inflammation, 36; 1295-1303 (2013)
Ito T, Connett JM, Kunkel SL, Matsukawa A.
The linkage of innate and adaptive immune response during granulomatous development. Front Immunol, 4; 10 (2013)
Yoshimura T, Howard OM, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim JJ, Wang JM.
Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells. PLoS One, 8; e58791 (2013)
Yashiro M, Tsukahara H, Matsukawa A, Yamada M, Fujii Y, Nagaoka Y, Tsuge M, Yamashita N, Ito T, Yamada M, Masutani H, Yodoi J, Morishima T.
Redox-active protein thioredoxin-1 administration ameliorates influenza A virus (H1N1)-induced acute lung injury in mice. Crit Care Med, 41; 171-181 (2013)
Cavassani KA, Moreira AP, Habiel D, Ito T, Coelho AL, Allen RM, Hu B, Raphelson J, Carson WF 4th, Schaller MA, Lukacs NW, Omary MB, Hogaboam CM, Kunkel SL.
Toll like receptor 3 plays a critical role in the progression and severity of acetaminophen-induced hepatotoxicity. PLoS One, 8; e65899 (2013)
Sato Y, Takeuchi M, Takata K, Ohno K, Iwaki N, Orita Y, Goto N, Hida AI, Iwamoto T, Asano N, Ito T, Hanakawa H, Yanai H, Yoshino T.
Clinicopathologic analysis of IgG4-related skin disease. Mod Pathol, 4; 523-532 (2013)
Hanakawa H, Orita Y, Sato Y, Takeuchi M, Ohno K, Iwaki N, Ito T, Nishizaki K, Yoshino T.
Cutting needle biopsy combined with immunohistochemical study of myeloperoxidase for the diagnosis of histiocytic necrotizing lymphadenitis. Acta Otolaryngol, 133; 1328-1332 (2013)
Rezano A, Kuwahara K, Yamamoto-Ibusuki M, Kitabatake M, Moolthiya P, Phimsen S, Suda T, Tone S, Yamamoto Y, Iwase H, Sakaguchi N.
Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival. BMC Cancer, 13; 562 (2013)
Ommori R, Ouji N, Mizuno F, Kita E, Ikada Y, Asada H.
Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteria. Microb Pathog, 56; 35-39 (2013)
Ito T, Connett JM, Kunkel SL, Matsukawa A.
Notch system in the linkage of innate and acquired immunity. J Leukoc Biol, 92; 59-65 (2012)
Ito T, Matsukawa A.
Notch system in influenza A/H1N1 virus infection. Inflammation and Regeneration, 32; 132-136 (2012)
Wakabayashi H, Ito T, Fushimi S, Nakashima Y, Itakura J, Quiying L, Win MM, Cuiming S, Chen C, Sato M, Mino M, Ogino T, Makino H, Yoshimura A, Matsukawa A.
Spred-2 deficiency exacerbates acetoaminophen-induced hapatoxicity in mice. Clin Immunol, 144; 272-282 (2012)
Fushimi S, Ogino T, Aoki K, Itakura J, Ito T, Oeda T, Yanai H, Matsukawa A.
Prostatic stromal tumor of uncertain malignant potential (STUMP) with unrecognized growth pattern. Pathol Int, 62; 69-71 (2012)
Demoor T, Petersen BC, Morris S, Mukherjee S, Ptaschinski C, De Almeida Nagata DE, Kawai T, Ito T, Akira S, Kunkel SL, Schaller MA, Lukacs NW.
IPS-1 signaling has a nonredundant role in mediating antiviral responses and the clearance of respiratory syncytial virus. J Immunol, 189; 5942-5953 (2012)
Kitabatake M, Toda T, Kuwahara K, Igarashi H, Ohtsuji M, Tsurui H, Hirose S, Sakaguchi N.
Transgenic overexpression of G5PR that is normally augmented in centrocytes impairs the enrichment of high-affinity antigen-specific B cells, increases peritoneal B-1a cells, and induces autoimmunity in aged female mice. J Immunol, 189; 1193-1120 (2012)
Kuwahara K, Nakaya T, Phimsen S, Toda T, Kitabatake M, Kaji T, Takemori T, Watanabe T, Sakaguchi N.
Lyn signaling to upregulate GANP is critical for the survival of high-affinity B cells in germinal centers of lymphoid organs. J Immunol, 189; 3472-3479 (2012)
Phimsen S, Kuwahara K, Nakaya T, Ohta K, Suda T, Rezano A, Kitabatake M, Vaeteewoottacharn K, Okada S, Tone S, Sakaguchi N.
Selective cell death of p53-insufficient cancer cells is induced by knockdown of the mRNA export molecule GANP. Apoptosis, 17; 679-690 (2012)
Nakaya T, Kuwahara K, Ohta K, Kitabatake M, Toda T, Takeda N, Tani T, Kondo E, Sakaguchi N.
Critical Role of Pcid2 in B Cell Survival through the Regulation of MAD2 Expression. J Immunol, 185; 5180-5187 (2012)
Ito T, Allen RM, Carson WF 4th, Schaller M, Cavassani KA, Hogaboam CM, Lukacs NW, Matsukawa A, Kunkel SL.
The critical role of Notch ligand Delta-like 1 in the pathogenesis of influenza A virus (H1N1) infection. PLoS Pathog, 7; e1002341 (2011)
Ito T, Carson WF 4th, Cavassani KA, Connett JM, Kunkel SL.
CCR6 as a mediator of immunity in the lung and gut. Exp Cell Res, 317; 613-619 (2011)
Carson IV WF, Ito T, Schaller M, Cavassani KA, Chensue SW, Kunkel SL.
Dysregulated cytokine expression by CD4+ T cells from post-septic mice modulates both Th1 and Th2-mediated granulomatous lung inflammation. PLoS One, 6; e20385 (2011)
Frantz FG, Ito T, Cavassani KA, Hogaboam CM, Silva CL, Kunkel SL, Faccioli LH.
Therapeutic DNA vaccine reduces Schistosoma mansoni-induced tissue damage through cytokines balance and decreased migration of myofibroblasts. Am J Pathol, 179; 223-229 (2011)
Schaller MA, Logue H, Mukherjee S, Lindell DM, Coelho AL, Lincoln P, Carson WF 4th, Ito T, Cavassani KA, Chensue SW, Hogaboam CM, Lukacs NW, Kunkel SL.
Delta-like 4 differentially regulates murine CD4 T cell expansion via BMI1. PLoS One, 5; e12172 (2010)
Carson IV WF, Cavassani KA, Ito T, Schaller M, Ishii M, Dou Y, Kunkel SL.
Impaired CD4+ T cell proliferation and effector function correlates with repressive histone methylation events in a mouse of severe sepsis, Eur J Immunol, 40; 998-1010 (2010)
Maeda K, Singh SK, Eda K, Kitabatake M, Pham P, Goodman MF, Sakaguchi N.
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. J Biol Chem, 285; 23945-23953 (2010)
Okamoto N, Kuwahara K, Ohta K, Kitabatake M, Takagi K, Mizuta H, Kondo E, Sakaguchi N.
Germinal center-associated nuclear protein (GANP) is involved in mRNA export of Shugoshin-1 required for centromere cohesion and in sister-chromatid exchange. Genes Cells, 15; 471-484 (2010)
Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E.
Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance. Am J Physiol Lung Cell Mol Physiol, 298; L67-78 (2010)
Ouji Y, Yoshikawa M, Nishiofuku M, Ouji-Sageshima N, Kubo A, Ishizaka S.
Effects of Wnt-10b on proliferation and differentiation of adult murine skin-derived CD34 and CD49f double-positive cells. J Biosci Bioeng, 110; 487-490 (2010)
Ouji Y, Yoshikawa M, Moriya K, Nishiofuku M, Ouji-Sageshima N, Matsuda R, Nishimura F, and Ishizaka S.
Isolation and characterization of murine hepatocytes following collagenase infusion into left ventricle of heart. J. Biosci Bioeng, 110; 217-222 (2010)
Ito T, Schaller M, Hogaboam CM, Standiford TJ, Sandor M, Lukacs NW, Chensue SW, Kunkel SL.
TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4. J Clin Invest, 119; 33-46 (2009)
Ito T, Schaller M, Raymond T, Joshi AD, Coelho AL, Frantz FG, Carson IV WF, Hogaboam CM, Lukacs NW, Standiford TJ, Phan SH, Chensue SW, Kunkel SL.
Toll-like Receptor 9 Activation is a Key Mechanism for the Maintenance of Chronic Lung Inflammation. Am J Respir Crit Care Med, 180; 1227-1238 (2009)
Ramprakash H, Ito T, Kunkel SL, Hogaboam CM.
Toll-like receptor 9 modulates immune responses to Aspergillus fumigatus conidia in immunodeficient and allergic mice. Infect Immun, 77; 108-119 (2009)
Sakaguchi N, Toda T, Nakaya T, Kitabatake M, Maeda K, Kuwahara K.
Generation of high affinity monoclonal antibodies for the prevention of HIV infection. Recent Pat DNA Gene Seq, 3; 88-95 (2009)
Toda T, Kitabatake M, Igarashi H, Sakaguchi N.
The immature B-cell subpopulation with low RAG1 expression is increased in the autoimmune New Zealand Black mouse. Eur J Immunol, 39; 600-11 (2009)
Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E.
Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance. Am J Physiol Lung Cell Mol Physiol, 298; L67-78 (2009)
Suzaki Y, Hamada K, Nomi T, Ito T, Sho M, Kai Y, Nakajima Y, Kimura H.
A small-molecule compound targeting CCR5 and CXCR3 prevents airway hyperresponsiveness and inflammation. Eur Respir J, 31; 783-789 (2008)
Ishii M, Hogaboam CM, Joshi A, Ito T, Fong DJ, Kunkel SL.
CC chemokine receptor 4 modulates Toll-like receptor 9-mediated innate immunity and signaling. Eur J Immunol, 38; 2290-2302 (2008)
Yasui F, Kai C, Kitabatake M, Inoue S, Yoneda M, Yokochi S, Kase R, Sekiguchi S, Morita K, Hishima T, Suzuki H, Karamatsu K, Yasutomi Y, Shida H, Kidokoro M, Mizuno K, Matsushima K, and Kohara M.
Prior immunization with SARS-CoV nucleocapsid protein causes severe pneumonia in mice infected with SARS-CoV. J Immunol, 181; 6337-6348 (2008)
Sawanobori Y, Ueha S, Kurachi M, Shimaoka T, Talmadge JE, Abe J, Shono Y, Kitabatake M, Kakimi K, Mukaida N, Matsushima.
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Ueha S, Yoneyama H, Hontsu S, Kurachi M, Kitabatake M, Abe J, Yoshie O, Shibayama S, Sugiyama T, Matsushima K.
CCR7 mediates the migration of Foxp3+ regulatory T cells to the paracortical areas of peripheral lymph nodes through high endothelial venules. J Leukoc Biol, 82; 1230-1238 (2008)
Ishitani A, Sageshima N, Nakanishi M, Hatake K.
Can soluble HLA-G protein be a marker for the seclection of IVF embros? J Mamm Ova Res, 25; 17-25 (2008)
Ito T, Schaller M, Hogaboam CM, Standiford TJ, Chensue SW, Kunkel SL.
TLR9 activation is a key event for the maintenance of a mycobacterial antigen-elicited pulmonary granulomatous response. Eur J Immunol, 37; 2847-2855 (2007)
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Exposure of pregnant mice to an air pollutant aerosol increases asthma susceptibility in offspring. J Toxicol Environ Health A, 70; 688-695 (2007)
Nakano A, Yoneyama H, Ueha S, Kitabatake M, Ishikawa S, Kawase I, Sugiyama H, Matsushima K.
Intravenous administration of MIP-1alpha with intra-tumor injection of P. acnes shows potent anti-tumor effect. Int Immunopharmacol, 7; 845-857 (2007)
Ueha S, Murai M, Yoneyama H, Kitabatake M, Imai T, Shimaoka T, Yonehara S, Ishikawa S, Matsushima K.
Intervention of MAdCAM-1 or fractalkine alleviates graft-versus-host reaction associated intestinal injury while preserving graft-versus-tumor effects. J Leukoc Biol, 81; 176-185 (2007)
Kitabatake M, Inoue S, Yasui F, Yokochi S, Arai M, Morita K, Shida H, Kidokoro M, Murai F, Le MQ, Mizuno K, Matsushima K, Kohara M.
SARS-CoV spike protein-expressing recombinant vaccinia virus efficiently induces neutralizing antibodies in rabbits pre-immunized with vaccinia virus. Vaccine, 25; 630-637 (2007)
Sageshima N, Shobu T, Awai K, Hashimoto H, Yamashita M, Takeda N, Odawara Y, Nakanishi M, Hatake K, Ishitani A.
Soluble HLA-G is absent from human embryo cultures: a reassessment of sHLA-G detection methods. J Reprod Immunol, 75; 11-22 (2007)
Shobu T, Sageshima N, Tokui H, Omura M, Saito K, Nagatsuka Y, Nakanishi M,Hayashi Y, Hatake K, Ishitani A.
The surface expression of HLA-F on decidual trophoblasts increases from mid to term gestation. J Reprod Immunol, 72; 18-32 (2006)
Pyo CW, Williams LM, Moore Y, Hyodo H, Li SS, Zhao LP, Sageshima N, Ishitani A, Geraghty DE.
HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype structure and variation spanning the nonclassical class I genes. Immunogenetics, 58;241-251 (2006)
Ito T, Hamada K, Suzaki Y, Matsui N, Kita E, Kimura H.
Subcutaneous vaccination of Mycobacterium bovis Bacillus Calmette-Guerin attenuates allergic inflammation in a murine model of asthma. Allergology International, 4; 601-609 (2005)
Suzaki Y, Hamada K, Sho M, Ito T, Miyamoto K, Akashi S, Kashizuka H, IkedaN, Nakajima Y, Iwase M, Homma I, Kobzik L, Kimura H.
A potent antiangiogenic factor, endostatin prevents the development of asthma in a murine model. J Allergy Clin Immunol, 116; 1220-1227 (2005)
Akadegawa K, Ishikawa S, Sato T, Suzuki J, Yurino H, Kitabatake M, Ito T, Kuriyama T, Matsushima K.
Breakdown of mucosal immunity in the gut and resultant systemic sensitization by oral antigens in a murine model for systemic lupus erythematosus. J Immunol, 174; 5499-5506 (2005)
Sato T, Ishikawa S, Akadegawa K, Ito T, Yurino H, Kitabatake M, Yoneyama H,Matsushima K.
Aberrant B1 cell migration into the thymus results in activation ofCD4 T cells through its potent antigen-presenting activity in the development of murine lupus. Eur J Immunol, 34; 3346-3358 (2004)
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Endocrine disruptors (environmental estrogens) enhance autoantibody production by B1 cells. Toxicol Sci, 81; 139-147 (2004)
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Defective B1 cell homing to the peritoneal cavity and preferential recruitment of B1 cells in the target organs in a murine model for systemic lupus erythematosus. J Immunol, 172; 3628-3634 (2004)
Hontsu S, Yoneyama H, Ueha S, Terashima Y, Kitabatake M, Nakano A, Ito T, Kimura H, Matsushima K.
Visualization of naturally occurring Foxp3+ regulatory T cells in normal and tumor-bearing mice. Int Immunopharmacol, 4; 1785-1793 (2004)
Yoneyama H, Matsuno K, Zhang Y, Nishiwaki T, Kitabatake M, Ueha S, Narumi S, Morikawa S, Ezaki T, Lu B, Gerard C, Ishikawa S, Matsushima K.
Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules. Int Immunol, 16; 915-928 (2004)
Ishitani A, Sageshima N, Lee N, Dorofeeva N, Hatake K, Marquardt H, Geraghty DE.
Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition. J Immunol,171; 1376-1384 (2003)
Sageshima N, Ishitani A, Omura M, Akasaki M, Umekage H, Katabuchi H, Okamura H, Hatake K.
Necrotic feature of the trophoblasts lacking HLA-G expression in normal and pre-eclamptic placentas. Am J Reprod Immunol, 49; 174-182 (2003)
Onai N, Kitabatake M, Zhang YY, Ishikawa H, Ishikawa S, Matsushima K.
Pivotal role of CCL25 (TECK)-CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes. Int Immunol, 14; 687-694 (2002)
Grimsley C, Kawasaki A, Gassner C, Sageshima N, Nose Y, Hatake K, Geraghty DE, Ishitani A.
Definitive high resolution typing of HLA-E allelic polymorphisms: Identifying potential errors in existing allele data. Tissue Antigens, 60; 206-212 (2002)
Ishitani A, Kishida M, Sageshima N, Yashiki S, Sonoda S, Hayami M, Smith AG, Hatake K.
Re-examination of HLA-G polymorphism in African Americans. Immunogenetics, 49; 808-811 (1999)
